19: Bret Weinstein - The Prediction and the DISC: Difference between revisions

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'''Eric:''' Right.  
'''Eric:''' Right.  


'''Bret:''' -in my paper, which is the natural thing to do. And she says, “we're not going to publish it. We're going to keep the information “in house.” That was her phrase. I was too young to understand what the hell she was talking about.
'''Bret:''' -in my paper, which is the natural thing to do. And she says, “we're not going to publish it. We're going to keep the information <em>in-house</em>. That was her phrase. I was too young to understand what the hell she was talking about.


'''Eric:''' I'll be honest, I'm 54 and I don't quite understand it myself.  
'''Eric:''' I'll be honest, I'm 54 and I don't quite understand it myself.  
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'''Eric:''' -I have a stream of papers I can get at.
'''Eric:''' -I have a stream of papers I can get at.


'''Bret:''' ‘-then I can start predicting other results. Nobody will know how I am doing that thing. I will look like a super genius.’ And so, holding it [italics]in house[italics] is a mechanism for a whole slew of papers.
'''Bret:''' ‘-then I can start predicting other results. Nobody will know how I am doing that thing. I will look like a super genius.’ And so, holding it <em>in-house</em> is a mechanism for a whole slew of papers.


'''Eric:''' -to be, to be 100%-you can afford to bend over backwards and not make inferences. Let's say the following: Holding it [italics]in house[italics] is a seemingly inexplicable decision in science, but for the fact that it fits at least one story of this kind, which is that it is consistent with wishing to publish a stream, rather than the source of the information that would allow you—so you can either do one discovery or you can do a stream of predictions, and that makes a certain amount of sense, given the ruthlessly competitive grant-winning environment. And we don't know exactly what happened, but there is no world that I know of in which you're allowed to hold back that kind of information because, in part, of what's on the line.  
'''Eric:''' -to be, to be 100%-you can afford to bend over backwards and not make inferences. Let's say the following: Holding it <em>in-house</em> is a seemingly inexplicable decision in science, but for the fact that it fits at least one story of this kind, which is that it is consistent with wishing to publish a stream, rather than the source of the information that would allow you—so you can either do one discovery or you can do a stream of predictions, and that makes a certain amount of sense, given the ruthlessly competitive grant-winning environment. And we don't know exactly what happened, but there is no world that I know of in which you're allowed to hold back that kind of information because, in part, of what's on the line.  


'''Bret:''' Right. So—
'''Bret:''' Right. So—
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'''Bret:''' Right.
'''Bret:''' Right.


'''Eric:''' OK? -It used to be that the editor of a journal took responsibility for the quality of the journal, which is why we had things like Nature crop up in the first place, because they had courageous, knowledgeable, forward thinking editors. And so I just want to be very clear, because there's a mind virus out there that says ‘peer review is the [italics]sine qua non[italics] of scientific excellence, yada, yada, yada, bullshit, bullshit, bullshit’. And if you don't believe me, go back and learn that this is a recent invasive problem in the sciences.
'''Eric:''' OK? -It used to be that the editor of a journal took responsibility for the quality of the journal, which is why we had things like Nature crop up in the first place, because they had courageous, knowledgeable, forward thinking editors. And so I just want to be very clear, because there's a mind virus out there that says ‘peer review is the <em>sine qua non</em> of scientific excellence, yada, yada, yada, bullshit, bullshit, bullshit’. And if you don't believe me, go back and learn that this is a recent invasive problem in the sciences.


'''Bret:''' Recent invasive problem that has no justification for existing in light of the fact that—
'''Bret:''' Recent invasive problem that has no justification for existing in light of the fact that—
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(01:40:36)
(01:40:36)


'''Eric:''' I want to back up because I think this is a really important part of the story. What you're saying is that if you take an organism that has an expected, let's say, 40 year lifetime, it's very expensive timewise to say, ‘We ran this experiment and found that there was no immediate damage that was visible, but towards the very end of their lives we saw a marked increase in morbidity,’ or-
'''Eric:''' I want to back up because I think this is a really important part of the story. What you're saying is that if you take an organism that has an expected, let's say, 40-year lifetime, it's very expensive timewise to say, ‘We ran this experiment and found that there was no immediate damage that was visible, but towards the very end of their lives we saw a marked increase in morbidity,’ or-


'''Bret:''' Yeah, I mean if you took a drug and it knocked 15 years off your life on average, that might not show up in any notable way in a short term study.
'''Bret:''' Yeah, I mean if you took a drug and it knocked 15 years off your life on average, that might not show up in any notable way in a short term study.
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'''Eric:''' Got it.
'''Eric:''' Got it.


'''Bret:''' Your eye cells don't. Now note, all of the tissues I've just mentioned,-when's the last time you heard about anybody having, cancer of the cartilage, of their knee, cancer of the heart?
'''Bret:''' Your eye cells don't. Now note, all of the tissues I've just mentioned-when's the last time you heard about anybody having cancer of the cartilage, of the knee, cancer of the heart?


'''Eric:''' If they get brain cancer, it tends to be glial—
'''Eric:''' If they get brain cancer, it tends to be glial—
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'''Bret:''' Yeah. And the people who man it don't even know what they are, for most of them. They don't know what role they're playing.  
'''Bret:''' Yeah. And the people who man it don't even know what they are, for most of them. They don't know what role they're playing.  


'''Eric:''' Look, you see the same thing with like string theory because none of the reporters are actually string theorists, so they're dependent upon this. You saw this with this woman alleging that she had the Epstein story three years earlier, but that the editors said, well, we might lose access to the baby pictures of the Royal grandchildren, you're seeing this with catch and kill. There's this, I mean, I want you to take this seriously. You're just showing a part of what I'm calling the DISC, the Distributed Idea Suppression Complex. We have 50 years of such stories, and it happens that in our family, three out of four of us created such a story trying to get a PhD. And the idea for me is that every time you have to go into some closed system, there's a committee meeting, or there's a blue ribbon commission, or there's a peer review process, or there's a-what do they call them-the panels—study groups, for grants. That's where the DISC lives. We know that it's localized to the things that protect the integrity of science. It's an autoimmune disease, where what we have is an ability to stop highly disruptive ideas from getting a hearing in the general population of experts, by virtue of the fact that a carefully chosen group of experts can stop publication. Because look, if you're wrong about this stuff, there's a cost.  It's not cheap.  
'''Eric:''' Look, you see the same thing with like string theory because none of the reporters are actually string theorists, so they're dependent upon this. You saw this with the woman alleging that she had the Epstein story three years earlier, but that the editors said, well, we might lose access to the baby pictures of the Royal grandchildren, you're seeing this with catch and kill. There's this, I mean, I want you to take this seriously. You're just showing a part of what I'm calling the DISC, the Distributed Idea Suppression Complex. We have 50 years of such stories, and it happens that in our family, three out of four of us created such a story trying to get a PhD. And the idea for me is that every time you have to go into some closed system, there's a committee meeting, or there's a blue ribbon commission, or there's a peer review process, or there's a-what do they call them-the panels—study groups, for grants. That's where the DISC lives. We know that it's localized to the things that protect the integrity of science. It's an autoimmune disease, where what we have is an ability to stop highly disruptive ideas from getting a hearing in the general population of experts, by virtue of the fact that a carefully chosen group of experts can stop publication. Because look, if you're wrong about this stuff, there's a cost.  It's not cheap.  


'''Bret:''' No, I mean, in fact, it would have been career ending, I'm pretty sure, had I been—  
'''Bret:''' No, I mean, in fact, it would have been career ending, I'm pretty sure, had I been—  
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'''Eric:''' So this is the delta between a wild type and laboratory mice.  
'''Eric:''' So this is the delta between a wild type and laboratory mice.  


'''Bret:''' Yeah. And I'm shocked because she's told me they're keeping it [italics]in house,[italics] and instead they've got a paper [and] that they are-she says-in final revisions. They are that day submitting their final revisions to nucleic acid research with their paper. And I say, Carol, can I see the paper? And she says yes. And she sends me a manuscript, not the pre-print of the paper. She sends me a manuscript of the paper, no acknowledgements, no figures. And I contact her and I say, can I see the acknowledgements and the figures? She sends them to me, and I contact her and I say Carol, I'm disturbed. This was my hypothesis that you were testing. I should probably be an author on this paper, but at the very least I need to be an acknowledgement in this paper so that I can go back and point to it and say that was-
'''Bret:''' Yeah. And I'm shocked because she's told me they're keeping it <em>in-house </em> and instead they've got a paper [and] that they are-she says-in final revisions. They are that day submitting their final revisions to nucleic acid research with their paper. And I say, Carol, can I see the paper? And she says yes. And she sends me a manuscript, not the pre-print of the paper. She sends me a manuscript of the paper, no acknowledgements, no figures. And I contact her and I say, can I see the acknowledgements and the figures? She sends them to me, and I contact her and I say Carol, I'm disturbed. This was my hypothesis that you were testing. I should probably be an author on this paper, but at the very least I need to be an acknowledgement in this paper so that I can go back and point to it and say that was-


'''Eric:''' It changes everything that it was a prediction. It wasn't just something that was stumbled upon.  
'''Eric:''' It changes everything that it was a prediction. It wasn't just something that was stumbled upon.  
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